Sensor can detect scarred or fatty liver tissue

MIT engineers have developed a diagnostic tool, based on nuclear magnetic resonance (NMR), that could be used to detect fatty liver disease and liver fibrosis. Credit: Massachusetts Institute of Technology

About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure.

Currently there is no easy way to diagnose either fatty or . However, MIT engineers have now developed a , based on nuclear magnetic resonance (NMR), that could be used to detect both of those conditions.

“Since it’s a , you could screen people even before they have obvious symptoms of compromised liver, and you would be able to say which of these patients had fibrosis,” says Michael Cima, the David H. Koch Professor of Engineering in MIT’s Department of Materials Science and Engineering, a member of MIT’s Koch Institute for Integrative Cancer Research, and the senior author of the study.

The device, which is small enough to fit on a table, uses NMR to measure how water diffuses through tissue, which can reveal how much fat is present in the tissue. This kind of diagnostic,

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Cellular Vitamin Is The Best Primary Nutrition

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YOU PERCEIVE AND AGREE THAT YOUR USE AND THE AVAILABILITY OF THE COMPANIES INVOLVE THE GATHERING, STORAGE, PROCESSING, USE AND DISCLOSURE OF INFORMATION AND CONSUMER DATA, TOGETHER WITH THE SWITCH OF INFORMATION AND KNOWLEDGE TO DIFFERENT COMPANIES AND TERRITORIES, AS STATED IN THE PRIVATENESS POLICY. The aforementioned facts spotlight the growing demand for health and wonder merchandise amongst people of all ages and cultures. As …

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Out of many COVID-19 tests, which one to choose?

Various diagnostic techniques can be used for sensing the RNA of SARS-CoV-2. Credit: Saadet Alpdagtas and Elif Ilhan

Until a vaccine is available, curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined. However, the current diagnostic techniques vary in reliability and relevance, so an understanding of which test is most appropriate for a given circumstance is necessary to avoid false reports.

Researchers from Van Yuzuncu Yil University, Marmara University, Yildiz Technical University, and Istanbul Yeni Yuzyil University evaluated the available diagnostic techniques and determined key steps required for better testing moving forward. They present their findings in the journal APL Bioengineering.

“Rapid diagnosis and rapid isolation are the key factors for prevention of the pandemic,” said Oguzhan Gunduz, one of the authors.

Laboratory tests that target the virus’s genes—known as real-time reverse transcription-polymerase chain reaction assays—are currently the gold standard for testing. But according to the Food and Drug Administration, these could give false negatives.

These tests depend on the presence of antibodies, which may not have yet been developed in the early stages of infection. Since different antibodies appear at different stages, must be chosen to target

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Well being Fitness Diet

On the lookout for the solutions to longevity of life? When your mental well being suffers, it might turn out to be arduous to get pleasure from life. It’s possible you’ll start to really feel run down, both mentally and physically. Many of these adjustments could make it tougher to get pleasure from a balanced and rewarding life. Everyone can benefit from learning the right way to enhance and protect their mental health—whether or not they’ve experienced psychological sickness or a substance use problem. Support. Unless in any other case expressly said, we do not promise to provide you with any assist for the Services. If we give you help, it’s at our sole discretion and doesn’t mean that we’ll continue to provide you with assist in the future.

Few stop to assume, and even fewer teach concerning the impact of our mental beliefs upon the bodily physique. Our feelings and thoughts are alive with power. The dearth of feeling of exuberance and health is commonly due to a blockage of energy caused by the shortcoming to specific oneself in some area of our lives. This leads to frustration and dissatisfaction which break down the body’s pure rhythms, and if …

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Medical oddity ushers in discovery of unheard-of ‘immunity gene’ mutations—and a better way to screen them

Brain MRI of the 10-month old boy with anti-NMDAR encephalitis obtained on day 4. The axial T2 weighted image (T2WI) in A and B and the axial fluid attenuation inversion recovery (FLAIR) image in C and D showed high intensity regions in the bilateral thalamus. New “immunity gene” mutations that researchers discovered to be deleterious were found in the infant. Credit: Satoshi Okada

An infant’s odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.

The IRAK4 gene instructs the production of a protein that plays a key role in the early recognition and response to invading pathogens. Inherited in this gene can cause an immune system disorder that leaves the body susceptible to recurrent infections of pus-forming pyogenic bacteria. Cases of IRAK4 deficiency are quite rare and only about 10 familial instances were identified so far in Japan.

A Hiroshima University-led research team detected two novel IRAK4 mutations, c.29_30delAT (p.Y10Cfs*9) and c.35G>C (p.R12P), in a 10-month-old boy with anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis and human herpesvirus 6 (HHV6) reactivation. The p.Y10Cfs*9 and p.R12P variations were inherited

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Supporting Students Throughout Mental Well being Awareness Month & Beyond

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Click on Therapeutics is looking to enhance work on a web-based platform of prescription digital therapeutics.” The corporate’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to assist folks give up …

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New blood-test device monitors blood chemistry continually

The RT-ELISA prototype consists of three modules: in the first (bottom), blood from the subject is mixed with a solution containing beads of target protein-detecting probes and fluorescent detection antibodies. The second module (top-right) eliminates excess blood cells. And the third module (top-left), transfers the fluorescently labeled beads to a detection window for measurement by a high-speed camera. Credit: Caitlin Maikawa

For even the most routine of medical checkups, a blood test is often the first order of business. But, for all its diagnostic power, this common test provides only a snapshot of the blood during a single moment in time.

“A is great, but it can’t tell you, for example, whether insulin or glucose levels are increasing or decreasing in a patient,” said Tom Soh, a professor of electrical engineering and of radiology at Stanford. “Knowing the direction of change is important.”

Now, Soh, in collaboration with Eric Appel, an assistant professor of materials science and engineering, and colleagues have developed a technology that can provide this crucial piece of missing information. Their device, which they’ve dubbed the “Real-time ELISA,” is able to perform many tests very quickly and then stitch the individual results together to

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