Dependable oxygenation is conceivable with a brand new design for transportable concentrators

Credit score: CC0 Public Area

As well being staff around the globe present care to these contaminated with SARS-CoV-2 and its many variants, the shortages in medical oxygen proceed to deeply affect hospitals already stretched skinny. Whereas transportable oxygen concentrators have supplied some aid to many with respiratory misery, these machines typically don’t generate sufficient medical oxygen to fulfill the fluctuating calls for of a affected person with worsening signs, requiring them to be rehospitalized.

Anticipating the elevated want for higher oxygen concentrators because the combat towards COVID-19 rages on, researchers at Texas A&M College have laid a computational framework to design probably the most optimum concentrator to filter ambient air and produce oxygen that may scale with affected person demand.

“The COVID-19 pandemic has precipitated vital stress to our medical and emergency services and a surge of individuals requiring medical consideration, and hospitals have a restricted variety of air flow gear,” mentioned Dr. Faruque Hasan, affiliate professor and the Kim McDivitt ’88 and Phillip McDivitt ’87 Endowed College Fellow within the Artie McFerrin Division of Chemical Engineering. “However we may forestall some instances of hospitalization if we designed a extra superior, compact and transportable oxygen concentrator that has versatile

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New cellphone and good watch fashions can intervene with pacemakers and defibrillators

New analysis findings confirm FDA advice for sufferers with implanted medical units to maintain their good telephones and watches at the very least six inches away to keep away from interference with implanted medical units. Credit score: US Meals and Drug Administration

After reviews of good telephone and watch interference with implanted medical units, investigators affiliated with the Heart for Units and Radiological Well being (CDRH) on the US Meals and Drug Administration performed a research that helps the FDA advice that sufferers maintain any shopper digital units that will create magnetic interference, together with cell telephones and good watches, at the very least six inches away from implanted medical units, specifically pacemakers and cardiac defibrillators. Their findings seem in Coronary heart Rhythm, the official journal of the Coronary heart Rhythm Society, the Cardiac Electrophysiology Society, and the Pediatric & Congenital Electrophysiology Society.

“Making certain the security of our nation’s medical units is a cornerstone of our shopper safety mission, particularly as expertise continues to advance,” defined lead investigator Seth J. Seidman, MS, Analysis Electrical Engineer and EMC Program Advisor with the CDRH. “As a part of this work, the company reviewed just lately printed articles describing the likelihood

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Analyzing kidney stones utilizing geology and most cancers screening strategies

Fig.1 Protein distributions in a conically laminated calcium oxalate construction in a kidney stone. (a) Multicolor immunofluorescence staining picture. (b) IF picture of osteopontin. (c) IF picture of prothrombin fragment 1. (d) IF picture of calgranulin A. Credit score: Tanaka Y. et al., Scientific Studies

As much as 15% of individuals will expertise kidney stones, and for 50% of people who do, they may recur. It’s subsequently essential to grasp as a lot as attainable about how kidney stones type to enhance each prevention and therapy. A group of scientists led by Osaka College and Nagoya Metropolis College has reported a method that gives essentially the most detailed image of kidney stone elements but, shedding new gentle on the processes concerned in stone formation. Their findings are revealed in Scientific Studies.

Most kidney stones are primarily fabricated from calcium oxalate (CaOx) crystals. The CaOx makes up about 90% of the kidney stone—referred to as the mineral part—whereas a mix of quite a few completely different proteins supplies what is called the protein matrix.

Figuring out how these completely different elements work together is vital to understanding the advanced multi-step kidney stone-formation processes, and consequently offering higher outcomes for sufferers.

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FDA approves first nerve-stimulation machine to help stroke restoration


A primary-of-a-kind nerve stimulation remedy for individuals who have issues shifting their arms after a stroke has been permitted by the U.S. Meals and Drug Administration.

“Individuals who have misplaced mobility of their fingers and arms on account of ischemic stroke are sometimes restricted of their remedy choices for regaining motor operate,” defined Dr. Christopher Loftus. He’s performing director of the FDA’s Heart for Units and Radiological Well being’s Workplace of Neurological and Bodily Drugs Units. An ischemic stroke is attributable to blocked blood circulation to the mind.

“In the present day’s approval of the Vivistim Paired VNS System provides the primary stroke rehabilitation choice utilizing vagus nerve stimulation [VNS],” Loftus mentioned in an FDA information launch. “Used alongside rehabilitative train, this machine could supply profit to those that have misplaced operate of their higher limbs on account of ischemic stroke.”

The Vivistim System is a prescription remedy for ischemic stroke sufferers who’ve average to extreme issue shifting their arms and fingers. Used both at house or in a clinic, the system electrically stimulates the vagus nerve, which runs from the mind to the stomach.

An implantable generator that produces a gentle electrical pulse is implanted just below the pores

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‘ASCENT’ makes it simpler to review {the electrical} stimulation of nerves

The ASCENT instrument fashions how nerves can reply to electrical stimulation from customized electrodes. Nerve fibers seem in pink and blue, and the customized electrodes seem in grey. The underside graphic exhibits how the nerves seem when they’re activated. Credit score: Eric Musselman, Duke College

Biomedical engineers at Duke College have developed an open-source software program platform that automates 3D electrical nerve stimulation modeling. This may occasionally permit researchers to foretell how particular nerves will reply to totally different patterns of stimulation from customized electrodes.

The researchers hope the platform will assist researchers create correct fashions of recent therapies for a wide range of illnesses, together with diabetes, rheumatoid arthritis and heart problems.

Like a pacemaker for the center, nerve stimulation units are implanted within the physique and programmed to ship focused pulses of electrical energy into nerves. These electrical pulses could provoke or suppress alerts within the nerve, altering the regulation of organ features and probably treating illness. Nerve stimulation is a promising different to medicine in some circumstances..

This analysis seems on-line August 26 within the journal PLOS Computational Biology.

Sure electrical stimulation therapies, like vagus nerve stimulation, have already confirmed to be an efficient therapy for

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Digital actuality proven to scale back ache and anxiousness in kids

Credit score: Pixabay/CC0 Public Area

It is not a matter of 1 needle puncture. Many kids coming by means of the doorways of Kids’s Hospital Los Angeles are seen for persistent circumstances and sometimes require frequent visits. Painful procedures—like a blood draw or catheter placement—could cause anxiousness and worry in sufferers. Now, a research revealed in JAMA Community Open reveals that digital actuality can lower ache and anxiousness in kids present process intravenous (IV) catheter placement.

For practically twenty years, Jeffrey I. Gold, Ph.D., an investigator at The Saban Analysis Institute of Kids’s Hospital Los Angeles, has been investigating the usage of digital actuality (VR) as a method to assist kids present process painful medical procedures. His analysis reveals that the expertise can have highly effective results. VR works so properly that Kids’s Hospital Los Angeles now gives it routinely for blood attracts.

“Some sufferers do not even notice that their blood is being drawn,” says Dr. Gold, who can also be a Professor of Medical Anesthesiology, Pediatrics, and Psychiatry & Behavioral Sciences at The Keck College of Medication of USC. “Examine that to a toddler who’s panicking and screaming, and it is a no-brainer. We wish youngsters to really

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‘Secure and effectively tolerated’—the prototype respiratory gadget for COVID sufferers

The Leeds CPAP gadget — the fan is related to a respiratory circuit. Credit score: College of Leeds

A easy electrical fan is the important thing element of a low-cost, easy-to-use breathing-support gadget designed to deal with the surge in COVID circumstances in low to center revenue nations.

The gadget offers a type of oxygen remedy referred to as CPAP or steady constructive airway strain, which has proved efficient in serving to sufferers struggling to breathe due to average to extreme COVID.

In a paper revealed immediately (Tuesday, 24 Aug) within the journal Frontiers in Medical Expertise, the group growing the gadget say a pilot analysis involving ten wholesome volunteers has proven that it “…can be utilized safely with out inducing hypoxia (low ranges of oxygen in tissues) or hypercapnia (build-up of carbon dioxide within the bloodstream) and that its use was effectively tolerated by customers, with no antagonistic occasions reported”.

The researchers used the principals of “frugal innovation” to design and develop the respiratory help, to make sure the gadget stays easy whereas being each strong and in a position to meet scientific calls for in poorer-resourced well being settings.

A key innovation was to generate the required

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